Dermal Fillers For fine Lines and Wrinkles and lip (Restylane) Suitable for all skin types, Restylane is a natural treatment which is a non-animal based product. If you're worried about facial lines or wrinkles Restylane could be the answer. This simple, straightforward procedure is designed to 'fill out' and smooth away nose to mouth grooves, forehead lines, frown furrows, lipstick lines, acne pits, crows feet, chin and neck lines. Treatment can last between 6 to 12 months depending on each individual.